The observation and evaluation of curative effect of nasal mucosa dryness, hemorrhae and erosion].

Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery 2021 Jan 05

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Objective:To observe the curative effects of four kinds of plant extracts nasal spray mixture （myrtle oil, hyaluronic acid, fucoidan, anthocyanin） on 161 patients with nasal mucosa dryness, hemorrhae and erosion. Methods:① Diagnosis: patients with nasal dryness, erosive and hemorrhae nasal septum mucosa confirmed by patients' complaints and nasal endoscopic test; ② Evaluation: the severity of subjective symptoms was evaluated by VAS score method from 0 to 10 points; the degree of mucosal lesions was divided into 0-8 points by nasal endoscopic test. ③ Intranasal Intranasal administration: 2 times per-day with 2 sprays on each side of the nasal cavity, and no less than 6-8 weeks. In the patients which with allergic rhinitis were also given conventional oral administration of montelukast at the same time. ④ Follow up and curative effect evaluation: VAS and nasal endoscopic test scores that before and after treatment was statistically processed; the patients' own how feels the treatment were evaluated; finally, doctor made the final evaluation based on the combined results of subjective and objective evaluation results before and after treatment, the patients' satisfaction with treatment effect. Results:① There were significant differences in VAS scores of 161 patients before and after treatment （P<0.01）.② There were statistically significant differences in nasal endoscopic test scores of 104 patients before and after treatment （P<0.01）. ③ Patients' satisfaction survey showed the satisfied with the compliance, tolerance and treatment effect was 95%. Conclusion:The mixed nasal spray of four plant extracts can effectively improve the dryness, hemorrhae and erosion of nasal mucosal. Copyright© by the Editorial Department of Journal of Clinical Otorhinolaryngology Head and Neck Surgery.

Citation

Geng Xu, Minling Wu, Lei Yang, Tao Liu. The observation and evaluation of curative effect of nasal mucosa dryness, hemorrhae and erosion]. Lin chuang er bi yan hou tou jing wai ke za zhi = Journal of clinical otorhinolaryngology, head, and neck surgery. 2021 Jan 05;35(1):29-33