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Aim: The purpose of this meta-analysis was to evaluate the impact of oral health on quality of life in oral cancer patients (OCPs). Methods: PubMed, Scopus and Web of Science databases were searched for publications on oral health-related quality of life (OHRQoL) in OCP and the information was extracted according to the PRISMA guidelines. A random effect model was used to obtain the pooled standard mean differences of Oral Health Impact Profile (OHIP)-14 questionnaire responses in meta-analysis. Results: total of 12 research papers were analyzed and revealed poor OHRQoL in OCPs (standard mean difference: 2.53; 95% CI: 1.55-3.50; p < 0.00001) compared with healthy individuals due to the effects of oncotherapy. Moreover, OHRQoL deteriorated with combinations of different treatment modalities. Conclusion: Oral health and oncotherapy can affect the quality of life in OCPs.


Monal Yuwanati, Shailesh Gondivkar, Sachin C Sarode, Amol Gadbail, Ami Desai, Shubhangi Mhaske, Sandeep K Pathak, Mahalaqua N Khatib. Oral health-related quality of life in oral cancer patients: systematic review and meta-analysis. Future oncology (London, England). 2021 Mar;17(8):979-990

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PMID: 33541115

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