Cerebellar ataxia as a primary manifestation of neuropsychiatric systemic lupus erythematosus.

Marie Charmaine C Sy, Nikolai Gil D Reyes, Geraldine T Zamora, Marc Laurence L Fernandez

BMJ case reports 2021 Feb 04

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Acute cerebellar ataxia is a rare primary manifestation of neuropsychiatric systemic lupus erythematosus (NPSLE). We report a case of a 22-year-old woman who presented with gait instability, behavioural changes and new-onset seizures. The tempo of disease progression was explained by an autoimmune cause, eventually fulfilling the criteria for systemic lupus erythematosus. The patient's neurological symptoms improved markedly following administration of steroids and immunomodulators. A review of literature on cerebellar ataxia in NPSLE and a summary of all reported cases to date are also presented. © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Citation

Marie Charmaine C Sy, Nikolai Gil D Reyes, Geraldine T Zamora, Marc Laurence L Fernandez. Cerebellar ataxia as a primary manifestation of neuropsychiatric systemic lupus erythematosus. BMJ case reports. 2021 Feb 04;14(2)