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    Mastitis is a common disease in cows breeding. The milk quality will be significantly reduced with increased milk somatic cells, which often occurs in cows with mastitis. In this study, the influence of seasonal changes, age and lactation stages in the Dairy Herd Improvement (DHI) of cows was investigated. Then, the Dairy Herd Improvement (DHI) of cows with high somatic cell score (SCS) after melatonin treatment was systemically investigated. The results showed that melatonin significantly suppressed the milk somatic cell score under all of the tested conditions. The melatonin treatment also improved the milk nutritional value by reducing its fat but increasing its lactose and protein contents. The application of melatonin significantly improved the DHI. The beneficial effects of melatonin on DHI are likely attributed to the antioxidant and anti-inflammatory activities of melatonin.

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    Hao Wu, Songyang Yao, Tiankun Wang, Jun Wang, Kang Ren, Hai Yang, Wenkui Ma, Pengyun Ji, Yongqiang Lu, Hui Ma, Changwang He, Wenjuan Wei, Lu Zhang, Guoshi Liu. Effects of Melatonin on Dairy Herd Improvement (DHI) of Holstein Cow with High SCS. Molecules (Basel, Switzerland). 2021 Feb 05;26(4)

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    PMID: 33562613

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