John W Peters, Oliver Einsle, Dennis R Dean, Serena DeBeer, Brian M Hoffman, Patrick L Holland, Lance C Seefeldt
Science (New York, N.Y.) 2021 Feb 12Kang et al (Reports, 19 June 2020, p. 1381) report a structure of the nitrogenase MoFe protein that is interpreted to indicate binding of N2 or an N2-derived species to the active-site FeMo cofactor. Independent refinement of the structure and consideration of biochemical evidence do not support this claim. Copyright © 2021, American Association for the Advancement of Science.
John W Peters, Oliver Einsle, Dennis R Dean, Serena DeBeer, Brian M Hoffman, Patrick L Holland, Lance C Seefeldt. Comment on "Structural evidence for a dynamic metallocofactor during N2 reduction by Mo-nitrogenase". Science (New York, N.Y.). 2021 Feb 12;371(6530)
PMID: 33574183
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