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    Both Ca2+ and reactive oxygen species (ROS) are double face entities, acting as signaling messengers or cell fate determinants according to their concentration and to spatial temporal restrictions. Recently, Beretta and colleagues found that ROS generated at ER-mitochondria contact sites (MAMs) support cell survival in stress conditions by decreasing inter-organelle Ca2+ transfer. Copyright © 2021 Elsevier Ltd. All rights reserved.


    Cristina Mammucari. In the right place at the right time: ROS and Ca2+ are allies in the battle for survival. Cell calcium. 2021 May;95:102354

    PMID: 33581406

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