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This study aimed to evaluate whether the antibiotic fidaxomicin has in vitro activity against Mycobacterium tuberculosis (Mtb). 38 fully drug-sensitive Mtb strains and 34 multidrug-resistant tuberculosis (MDR-TB) strains were tested using the microplate alamar blue assay (MABA) method to determine the minimum inhibitory concentrations (MICs) for fidaxomicin and rifampicin. Fidaxomicin has high in vitro activity against Mtb and is a potential drug to treat Mtb, and MDR-TB infections in particular.

Citation

Qing Sun, Shuqi Wang, Xinlei Liao, Guanglu Jiang, Hairong Huang, Hao Li, Guirong Wang. Fidaxomicin has high in vitro activity against Mycobacterium tuberculosis. Journal of medical microbiology. 2021 Mar;70(3)

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PMID: 33593474

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