Nuclear envelope lipids request border surveillance.

In this issue, Thaller et al. (2021. J. Cell Biol.https://doi.org/10.1083/jcb.202004222) explore how the ESCRT protein Chm7 is recruited to sites of defective nuclear pore assembly. They show that a lipid, phosphatidic acid, is enriched at pathological nuclear envelope herniations, where it promotes Chm7 recruitment for membrane surveillance and repair. © 2021 Köhler.

Citation

Alwin Köhler. Nuclear envelope lipids request border surveillance. The Journal of cell biology. 2021 Mar 01;220(3)

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PMID: 33599714

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