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The identification of discrete subclasses within the immunoglobulin G (IgG) isotype by Grey and Kunkel (1964. J. Exp. Med.https://doi.org/10.1084/jem.120.2.253) provided the framework for our current understanding of differential IgG subclass activity in protective and self-reactive immune responses. © 2021 Nimmerjahn and Ravetch.
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Falk Nimmerjahn, Jeffrey V Ravetch. Four keys to unlock IgG. The Journal of experimental medicine. 2021 Mar 01;218(3)
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PMID: 33600555
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