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Context: Amanita phalloides related toxicity from amatoxins can result in acute liver and multi-organ failure and is responsible for 90% of all mushroom poisoning death. However, more evidence is needed in regards to different management strategies.Case details: We present two cases of amanita mushroom ingestion who were treated with intravenous rifampicin.Discussion: Further study is needed to establish the efficacy and role of rifampicin in amatoxin related mushroom poisoning.


Rona Zuker-Herman, Roger Tong, Anselm Wong. Intravenous rifampicin use in the management of amanita phalloides toxicity. Clinical toxicology (Philadelphia, Pa.). 2021 Feb 19:1-4

PMID: 33605821

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