A New Potent Antimicrobial Metalloporphyrin.

Lu Jiang, Pei Lin Chee, Jian Gao, Ching Ruey Raymond Gan, Cally Owh, Rajamani Lakshminarayanan, Shan Jiang, T S Andy Hor, Xian Jun Loh

Chemistry, an Asian journal 2021 Apr 19

filter terms:

A series of bis-acryl functionalized porphyrins and their corresponding metalloporphyrins (M=Co, Mn) were synthesized and investigated for their antimicrobial properties through MIC screening and bacteria time-kill kinetic studies. The Mn(III) 4-(bis)methylphenyl-substituted-porphyrins showed superior batericidal activities even in the dark with low hemotoxicity and good cytotoxicity profile. © 2021 Wiley-VCH GmbH.

Citation

Lu Jiang, Pei Lin Chee, Jian Gao, Ching Ruey Raymond Gan, Cally Owh, Rajamani Lakshminarayanan, Shan Jiang, T S Andy Hor, Xian Jun Loh. A New Potent Antimicrobial Metalloporphyrin. Chemistry, an Asian journal. 2021 Apr 19;16(8):1007-1015