Correlation Engine 2.0
Clear Search sequence regions

  • catalysis (1)
  • triazoles (7)
  • Sizes of these terms reflect their relevance to your search.

    A straightforward and efficient methodology has been developed for the synthesis of 1,4,5-trisubstituted dicarbonyl 1,2,3-triazoles and 1,4-disubstituted sole-carbonyl 1,2,3-triazoles via a C-C bond cleavage process. The Regitz diazo transfer and C-C bond cleavage were the key steps of this transformation, which provided diverse carbonyl-substituted structural 1,2,3-triazoles. This reaction featured with excellent regioselectivity, wide functional group tolerance, and mild conditions.


    Xue Cui, Xueying Zhang, Wei Wang, Xia Zhong, Yinfeng Tan, Yan Wang, Jianlan Zhang, Youbin Li, Xuesong Wang. Regitz Diazo Transfer Reaction for the Synthesis of 1,4,5-Trisubstituted 1,2,3-Triazoles and Subsequent Regiospecific Construction of 1,4-Disubstituted 1,2,3-Triazoles via C-C Bond Cleavage. The Journal of organic chemistry. 2021 Mar 05;86(5):4071-4080

    Expand section icon Mesh Tags

    Expand section icon Substances

    PMID: 33620225

    View Full Text