Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer.

Sokratis Zormpas, Artemis Matsou, Diandra Monique Antunes, Chris Panos

BMJ case reports 2021 Feb 23

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In this case study, we explore a case of bilateral acute angle closure (AAC) attack detected in a 52-year-old female patient with no other ophthalmic background or predisposition to angle closure, following an increase of her regular sumatriptan dose used for migraine relief. Even though the initial presentation was misinterpreted as migraine attack, it nevertheless alerted the treating physicians to immediate cessation of the drug, allowing for the pertinent ocular symptomatology to be unveiled. Drug-induced bilateral AAC is a rare occurrence and can lead to significant ocular morbidity if not detected and treated early. Clinicians of emergency care should be aware of this uncommon association, as prompt ophthalmology input is vital. Interestingly, although it would be anticipated that people prone to angle closure attack after sumatriptan intake would exhibit symptoms after initiation of the drug, our patient suffered an attack while on long-term treatment and following dose increase. © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.

Citation

Sokratis Zormpas, Artemis Matsou, Diandra Monique Antunes, Chris Panos. Sumatriptan dose increase-induced acute angle closure glaucoma in chronic migraine sufferer. BMJ case reports. 2021 Feb 23;14(2)