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Somatostatin cell surface receptors are expressed in many different benign and malignant tumors and are often exploited for imaging and therapy of neuroendocrine tumors. A 17-year-old adolescent boy with clinicoradiologically diagnosed JNA (juvenile nasopharyngeal angiofibroma) also underwent 68Ga-DOTANOC PET to explore somatostatin cell surface receptors' expression and its theranostic potential. Fusion PET/MRI, a novel imaging technology, exactly depicted the anatomical extensions of the tumor with avid DOTANOC uptake. This software-based fusion technique is advantageous for easy early recurrence identification, better delineation from postoperative scar tissue, for planning the exact target volumes for stereotactic radiotherapy therapy of inoperable/residual/recurrent JNAs in the future. Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.

Citation

Pirabu Sakthivel, Alok Thakar, Sreedharan Thankarajan Arunraj, Ashu Seith Bhalla, Arun Prashanth, Rakesh Kumar. Fusion 68Ga-DOTANOC PET/MRI in Primary Juvenile Nasal Angiofibroma. Clinical nuclear medicine. 2021 Jul 01;46(7):e389-e390

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PMID: 33630795

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