Interferon-alpha-2a as a salvage treatment for hemorrhagic enteritis associated with Epstein-Barr Virus reactivation: a case report.

D Lankenau-Vela, F De la Garza-Salazar, P Colunga-Pedraza, D Jaime-Villalón

Acta gastro-enterologica Belgica 2021 Jan-Mar

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Epstein-Barr virus [EBV] is a virus that infects almost all humans worldwide. After the acute phase of the infection, it stays in a latent form in B lymphocytes. EBV reactivation tends to occur in immunosuppressed patients. EBV reactivation may involve the gastrointestinal tract ; it has been associated mainly with colitis, but hemorrhagic enteritis has been poorly reported. Treatment usually includes antivirals. However, our patient did not respond to conventional treatment, so interferon alpha-2a was given as a salvage treatment. To our knowledge, this is the first reported case of hemorrhagic enteritis associated to EBV reactivation treated successfully with interferon alpha-2a. © Acta Gastro-Enterologica Belgica.

Citation

D Lankenau-Vela, F De la Garza-Salazar, P Colunga-Pedraza, D Jaime-Villalón. Interferon-alpha-2a as a salvage treatment for hemorrhagic enteritis associated with Epstein-Barr Virus reactivation: a case report. Acta gastro-enterologica Belgica. 2021 Jan-Mar;84(1):129-130