Polyether ionophores residues in pasteurized milk marketed in the state of São Paulo, Brazil: Occurrence and exposure assessment.

Felipe Rodrigues Nogueira Silva, Mararlene Ulberg Pereira, Bernardete Ferraz Spisso, Adriana Pavesi Arisseto-Bragotto

Food research international (Ottawa, Ont.) 2021 Mar

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This paper aimed to survey the occurrence of six polyether ionophores (lasalocid, maduramycin, monensin, narasin, salinomycin and semduramycin) in pasteurized milk using a validated method by liquid chromatography coupled with tandem mass spectrometry (LC-MS/MS). For that, 40 samples of pasteurized milk, from seven brands, collected in six locations (supermarkets, grocery stores and greengrocers) in the metropolitan region of São Paulo and Campinas, São Paulo State, Brazil, were evaluated. Sampling included whole (18), skimmed (8) and semi-skimmed (10) milk as well as lactose-free (4) products. Only monensin antibiotic residues were found in the analyzed samples. This ionophore was confirmed in 45% of the samples and quantified in 32.5% at concentrations ranging from 0.1 to 0.27 μg kg-1. The positive samples were whole or semi-skimmed milk. Considering the levels of monensin reported in the present study and data on milk consumption in Brazil, an exposure assessment indicated that the intake of this antibiotic does not represent a risk to health. Copyright © 2020 Elsevier Ltd. All rights reserved.

Citation

Felipe Rodrigues Nogueira Silva, Mararlene Ulberg Pereira, Bernardete Ferraz Spisso, Adriana Pavesi Arisseto-Bragotto. Polyether ionophores residues in pasteurized milk marketed in the state of São Paulo, Brazil: Occurrence and exposure assessment. Food research international (Ottawa, Ont.). 2021 Mar;141:110015