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Xenopus models suggest convergence of gene signatures on neurogenesis in autism.

Kristen J Brennand, Michael E Talkowski

Neuron 2021 Mar 03


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  • autism (1)
  • estrogens (2)
  • neurogenesis (3)
  • pathogenesis (1)
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    Willsey et al. dissect phenotypes associated with in vivo disruption of ten ASD-associated genes using a hypothesis-free, parallelized approach in Xenopus tropicalis. These studies continue to implicate cortical neurons in ASD pathogenesis and suggest a convergence on functions related to neurogenesis. Copyright © 2021 Elsevier Inc. All rights reserved.

    Citation

    Kristen J Brennand, Michael E Talkowski. Xenopus models suggest convergence of gene signatures on neurogenesis in autism. Neuron. 2021 Mar 03;109(5):743-745

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    PMID: 33662268

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