Usual culture methods to identify pathogenic bacteria can be unsuccessful, particularly when working with fastidious organisms. We present a case of early periprosthetic knee joint infection with Ureaplasma parvum only identified using 16S ribosomal RNA PCR. This case represents the impact molecular methods of bacterial identification can have on clinical care allowing for more targeted antimicrobial therapy; something which is imperative in an era of increasing antimicrobial resistance. © BMJ Publishing Group Limited 2021. No commercial re-use. See rights and permissions. Published by BMJ.
Nicola Diane Ball, Susan Elizabeth Snape. Periprosthetic joint infection with Ureaplasma parvum detected by 16S rRNA PCR. BMJ case reports. 2021 Mar 05;14(3)
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PMID: 33674296
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