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Mycetoma is a chronic granulomatous disease that significant affects the subcutaneous tissue and deep structures. Mycetoma is caused by certain fungi (eumycetoma) or higher bacteria (actinomycetoma). The clinical presentation is variable and depends on the causative agent. For proper treatment and patient management, an accurate diagnosis of the species is mandatory. The disease mainly involves the extremities and it is rarely seen in the head and neck or other sites. In this communication, we present an interesting case of both invasive and aggressive mastoid bone eumycetoma caused by Madurella mycetomatis. Such cases are defied by complex challenges in finding effective surgical and medical treatments when the patient does not respond to both prolonged and different antifungal therapies. © The Author(s) 2021. Published by Oxford University Press on behalf of Royal Society of Tropical Medicine and Hygiene.


Abubaker Ahmed Yosif, Sahar Mubarak Bakhiet, Tagwa Hayder Abdalla, Najwa Adam Mhmoud, Emmanuel Edwar Siddig, Ahmed Hassan Fahal. Invasive, aggressive mastoid bone eumycetoma: a treatment challenge. Transactions of the Royal Society of Tropical Medicine and Hygiene. 2021 Apr 14;115(4):431-435

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PMID: 33682008

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