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    A rapid and label free aflatoxin B1 (AFB1) microfluid sensor was proposed and tested. The device was fabricated with hollow-core photonics crystal fiber infiltrated with the AFB1 solution. The autofluorescence emitting from the AFB1 molecules was detected. The sensor length was optimized. The AFB1 concentration was tested with a 4 cm long sensor. The best limit of detection was achieved as low as 1.34 ng/ml, which meets the test requirement of the national standards for AFB1 in food. The effectiveness of this sensor being applied in beer solution was also verified to be a little more sensitive than in aqueous solution. Compared with traditional AFB1 detection methods, the proposed single-ended device perfectly satisfies the demand of process control in alcoholic beverages manufacture.


    Huifang Chen, Fei Han, Bangning Mao, Ju Gu, Yudi Li, Chunliu Zhao, Yi Wang, Dongning Wang, Jing Zhan. Rapid and label free detection of aflatoxin B1 in alcoholic beverages with a microfluid fiber device. Applied optics. 2021 Mar 01;60(7):1924-1929

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    PMID: 33690282

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