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    Dectin-1 is known for promoting anti-fungal responses through the signaling molecule Card9. In this issue of Immunity, Deerhake et al. now report that during autoimmune neuroinflammation, Dectin-1 can promote a neuroprotective feed-forward pathway through Card9-independent upregulation of Oncostatin M. Copyright © 2021 Elsevier Inc. All rights reserved.

    Citation

    Angela A Wang, Jennifer L Gommerman. A totally OSM gift to astrocytes relieves inflammation. Immunity. 2021 Mar 09;54(3):401-403

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    PMID: 33691129

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