Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis.

B K Anupama, Parth Sampat, Harvir S Gambhir

Journal of investigative medicine high impact case reports 2021 Jan-Dec

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We report the case of a 71-year-old female who was incidentally found to have nonoliguric acute kidney injury on a routine workup for new-onset visual hallucination. Further history revealed inadvertent usage of nitrofurantoin for 3 months for an anticipated urological procedure. Renal biopsy demonstrated acute granulomatous interstitial nephritis. The renal function significantly improved following discontinuation of nitrofurantoin and corticosteroid administration. We highlight a rare association of nitrofurantoin with acute granulomatous interstitial nephritis through this case report.

Citation

B K Anupama, Parth Sampat, Harvir S Gambhir. Nitrofurantoin-Associated Acute Granulomatous Interstitial Nephritis. Journal of investigative medicine high impact case reports. 2021 Jan-Dec;9:23247096211001659