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Mycobacterium tuberculosis, the bacterium that causes tuberculosis, has long been an unpleasant neighbour of humans. Following transmission of the bacterium from patients with active infection, new hosts do not immediately develop symptoms, as M. tuberculosis initially remains quiescent. However, it is eventually triggered, leading to the infection of other individuals. Humans are the exclusive host, and the rapid proliferation of the human population worldwide along with increasing globalisation have contributed to the pathogen's persistence, as have the survival strategies employed by M. tuberculosis, especially its resistance to several antimicrobials. Defeating this enemy will require novel approaches. Copyright © 2021 The Authors. Published by Elsevier Ltd.. All rights reserved.


Mitsuko Seki, Hongjo Choi, Kyungjong Kim, Jake Whang, Joohon Sung, Satoshi Mitarai. Tuberculosis: A persistent unpleasant neighbour of humans. Journal of infection and public health. 2021 Apr;14(4):508-513

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PMID: 33743373

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