Brain lymphoma development related to a long lasting epidermoid cyst.

Epidermoid cysts (EC) are benign and slow growing lesions. A primary brain lymphoma development related to a EC is presented, second case described in literature. A woman 40 years old, harbouring a EC for more than 20 years, develops a fast growing brain lesion next to the EC. Surgery was performed and diagnosis was primary diffuse B cells lymphoma. Malignant transformation of EC has been described, usually to squamous cells carcinoma, and much less frequently, to another tumours. Inflammatory mechanisms have been advocated to explain this evolution. Chronic inflammation and lymphoma genesis are related, and this could be the mechanism behind this rare evolution of an EC. Even being benign lesions, EC can develop malignant tumours due to the chronic inflammation secondary to them. Copyright © 2021 Sociedad Española de Neurocirugía. Publicado por Elsevier España, S.L.U. All rights reserved.

Citation

Angel Horcajadas Almansa, Ana M Jorques Infante, Clara E Chamorro Santos, Ana M Román Cutillas. Brain lymphoma development related to a long lasting epidermoid cyst. Neurocirugia (English Edition). 2021 Mar 18

PMID: 33745844

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