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This chapter provides a general introduction to the dynorphins (DYNs)/kappa opioid receptor (KOR) system, including DYN peptides, neuroanatomy of the DYNs/KOR system, cellular signaling, and in vivo behavioral effects of KOR activation and inhibition. It is intended to serve as a primer for the book and to provide a basic background for the chapters in the book. © 2021. The Author(s), under exclusive license to Springer Nature Switzerland AG.


Catherine Cahill, Hugo A Tejeda, Mariana Spetea, Chongguang Chen, Lee-Yuan Liu-Chen. Fundamentals of the Dynorphins/Kappa Opioid Receptor System: From Distribution to Signaling and Function. Handbook of experimental pharmacology. 2022;271:3-21

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PMID: 33754230

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