Nrf2 a molecular therapeutic target for Astaxanthin.

Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Saeed Samarghandian

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 2021 May

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Astaxanthin (ATX) is a red pigment carotenoid present in shrimp, salmon, crab, and asteroidean. Several studies have corroborated the anti-oxidant efficacy of ATX. In addition, ATX has anti-inflammatory, anti-apoptotic and anti-proliferative properties. In the present review, we discuss the role of Nrf2 in mediating the anti-cancer, anti-aging, neuroprotective, lung-protective, skin-protective, cardioprotective, hepatoprotective, anti-diabetic and muscloprotective effects of ATX. Copyright © 2021. Published by Elsevier Masson SAS.

Citation

Zeynab Kohandel, Tahereh Farkhondeh, Michael Aschner, Saeed Samarghandian. Nrf2 a molecular therapeutic target for Astaxanthin. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. 2021 May;137:111374