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Hydroxylation and oxidation of nalidixic acid in the turtle Pseudemys scripta elegans.
T B Vree, J B Vree, A M Baars, J F Nouws, Y A Hekster
Department of Clinical Pharmacy, Sint Radboud Hospital, University of Nijmegen, The Netherlands.
The Veterinary quarterly 1988 JanSizes of these terms reflect their relevance to your search.
The turtle Pseudemys scripta elegans hydroxylates nalidixic acid into 7-hydroxynalidixic acid; this latter metabolite is oxidised into 7-carboxynalidixic acid. The elimination half-life of nalidixic acid in the turtle is 30 h. No glucuronides of nalidixic- and 7-hydroxynalidixic acid are formed, as they are in man.
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T B Vree, J B Vree, A M Baars, J F Nouws, Y A Hekster. Hydroxylation and oxidation of nalidixic acid in the turtle Pseudemys scripta elegans. The Veterinary quarterly. 1988 Jan;10(1):67-9
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PMID: 3376413
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