Correlation Engine 2.0
Clear Search sequence regions


Sizes of these terms reflect their relevance to your search.

Rapid and onsite detection of nitroaromatic explosive 2,4,6-trinitrotoluene (TNT) is very crucial for the safety and security of human life as well as for the environment. In this present work, we demonstrate the feasibility for employing Folic Acid (FA) as a fluorescent as well as a colorimetric probe for the detection of TNT. This probe was synthesized by a simple one-step process. The developed probe shows an emission maximum at 490 nm upon excitation at 420 nm. On adding TNT, the fluorescence of the FA probe is quenched. Also, it shows a good selectivity towards TNT over other similar organic compounds such as 4-nitrophenol (4-NP), 2,4-dinitrophenol (2,4-DNP) and picric acid (PA). The limit of detection (LoD) of TNT was found to be 1.9398 ┬ÁM. Colorimetric detection was conducted and paper strip assay was developed for the practical applications.

Citation

N S Vijila, M Athira, S Madanan Anju, A O Aswathy, J Jayakrishna, Mrudula Sreekumar, J S Anjali Devi, B Anjitha, Sony George. Folic Acid as a Bimodal Optical Probe for the Detection of TNT. Journal of fluorescence. 2021 Jul;31(4):933-940

Expand section icon Mesh Tags

Expand section icon Substances


PMID: 33782809

View Full Text