Recent Progress on the Synthesis of Chiral Sulfones.

Chiral sulfones extensively exist in drugs, agricultural chemicals, chiral organic intermediates, and functional materials. Their importance causes the rapid development of their synthetic methods in recent years. Many transition metal complex catalysts with chiral ligands and chiral organocatalysts are adopted in synthesis of chiral sulfones. Most of the methods to construct chiral sulfones are based on the reduction of unsaturated sulfones and the introduction of sulfone groups into unsaturated hydrocarbons. This review describes all classes of asymmetric reactions for synthesis of chiral sulfones. © 2021 The Chemical Society of Japan & Wiley-VCH GmbH.

Citation

Youming Huang, Jinyao Li, Hongyi Chen, Ze He, Qingle Zeng. Recent Progress on the Synthesis of Chiral Sulfones. Chemical record (New York, N.Y.). 2021 May;21(5):1216-1239

PMID: 33826228

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