Zhizhou Chen, Xiangwen Kong, Shengtong Niu, Shuang Yang, Jinggong Liu, Bolai Chen, Benlong Luo, Changyu Zhou, Chenglin Ding, Xinqiang Fang
Organic letters 2021 May 07N-Heterocyclic carbene-catalyzed asymmetric construction of cyclopentenones using enals and α-diketones is achieved, furnishing a series of highly functionalized cyclopentenones in a highly diastereo- and enantioselective manner. The protocol tolerates substrates with both aromatic and aliphatic groups, and further transformations of the products delivered a range of value-added molecules.
Zhizhou Chen, Xiangwen Kong, Shengtong Niu, Shuang Yang, Jinggong Liu, Bolai Chen, Benlong Luo, Changyu Zhou, Chenglin Ding, Xinqiang Fang. N-Heterocyclic Carbene-Catalyzed Asymmetric Synthesis of Cyclopentenones. Organic letters. 2021 May 07;23(9):3403-3408
PMID: 33844550
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