Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action.

Proteins represent the major building blocks of body tissues, and they regulate signaling involved in most cellular activities. Coronavirus disease 2019 (COVID-19) infection has been associated with high fatality, especially among older adults. The main cause of death is pulmonary tissue damage and multiple organ failure. The disease is associated with a hypercatabolic state that entails excessive protein loss. This review commentary sheds the light on hypoproteinemia in symptomatic/hospitalized COVID-19 with a special emphasis on its pathophysiology, screening, as well as its contribution to disease severity and adverse effects.

Citation

Amira Mohammed Ali, Hiroshi Kunugi. Hypoproteinemia predicts disease severity and mortality in COVID-19: a call for action. Diagnostic pathology. 2021 Apr 13;16(1):31

Mesh Tags

PMID: 33849598

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