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pH-dependent liposomal assays are often used to determine anion selectivity in transmembrane anion transport experiments. We discuss the validity and limitations of these assays, and provide guidelines for their use to avoid misleading results.


Xin Wu, Philip A Gale. Measuring anion transport selectivity: a cautionary tale. Chemical communications (Cambridge, England). 2021 Apr 22;57(33):3979-3982

PMID: 33885701

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