Serum glucose and potassium ratio as a predictive factor for prognosis of acute intracerebral hemorrhage.

The serum glucose/potassium ratio (GPR) is a potential prognostic predictor for acute brain injury-related diseases. We calculated the serum GPR in patients with acute intracerebral hemorrhage (ICH) and explored its prognostic value for long-term prognoses and ICH severity. This retrospective cohort study consecutively included 92 patients with ICH and 92 healthy controls. The National Institutes of Health Stroke Scale (NIHSS) score, Glasgow coma scale (GCS) score, and hematoma volume were used to assess severity. A modified Rankin Scale score > 2 at 90 days post-stroke was defined as a poor outcome. The serum GPR was significantly higher in patients than controls. The serum GPR was weakly correlated with the NIHSS score, GCS score, and hematoma volume. The serum GPR, GCS score, and hematoma volume were independently associated with poor outcomes. In the receiver operating characteristic curve analysis, the serum GPR remarkably discriminated patients at risk of poor outcomes at 90 days. The serum GPR significantly improved the prognostic predictive capability of hematoma volume and tended to increase that of the GCS score. Serum GPR is an easily obtained clinical variable for predicting clinical outcomes after ICH.

Citation

Xiao-Yu Wu, Yao-Kun Zhuang, Yong Cai, Xiao-Qiao Dong, Ke-Yi Wang, Quan Du, Wen-Hua Yu. Serum glucose and potassium ratio as a predictive factor for prognosis of acute intracerebral hemorrhage. The Journal of international medical research. 2021 Apr;49(4):3000605211009689

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PMID: 33906531

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