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Bone substitutes have been applied to treat osseous defects for a long time. To prevent implant related infection (IRI) and enhance bone healing functionalized biomaterials, antibiotics and osteoinductive substances have been introduced. This study gives an overview of the current available surface-coated bone substitutes and provides an outlook for future perspectives.


André Busch, Marcus Jäger, Constantin Mayer, Andrea Sowislok. Functionalization of Synthetic Bone Substitutes. International journal of molecular sciences. 2021 Apr 23;22(9)

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PMID: 33922517

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