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Epstein-Barr virus (EBV), a definite tumorigenic virus, is closely related to the development of nasopharyngeal cancer, gastric cancer, lymphoma and other tumors. EBV encodes a total of 44 mature microRNAs, which can regulate the expression of virus and host genes. EBV-encoded microRNAs and their regulated target molecules participate in the biological functions of tumor apoptosis, proliferation, invasion, and metastasis during tumorigenesis and development, and play an important role in the development of tumor.

Citation

Weiming Li, Weihong Yi, Dazhi Yang, Guiyuan Li. Epstein-Barr virus-encoded microRNAs involve in tumorigenesis and development. Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences. 2021 Mar 28;46(3):300-308

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PMID: 33927078

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