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Renal cyst is a common benign disease which is rare to progress from simple renal cyst to renal cell carcinoma. A 62-year-old woman who suffered a simple renal cyst for over 20 years complained intermittent lumbar in recent 2 years. At her latest admission, the cyst lesion displayed enhancement in the cystic wall by CT scan and cystic to partially solid change by ultrasound, so we did a partial nephrectomy and found that the cystic lesion had become a cyst-solid transition. The pathology turned out to be renal clear cell carcinoma. Although the canceration of a renal cyst is a small probability event, patients with a long history of a cyst, especially those with symptoms, need to seek for medical treatment in time, and if necessary, lesion biopsy or resection may be under consideration. IJCEP Copyright © 2021.


Yulong Lu, Jialin Hu, Ninghan Feng. Evolution of renal cyst to renal carcinoma: a case report and review of literature. International journal of clinical and experimental pathology. 2021;14(4):463-468

PMID: 33936368

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