Treatment Update of Port-Wine Stain: A Narrative Review.

Regina Fölster-Holst, Ratnakar Shukla, Martin Kassir, Hassan Galadari, Torello Lotti, Uwe Wollina, Stephan Grabbe, Mohamad Goldust

Journal of drugs in dermatology : JDD 2021 May 01

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Port-wine stain (PWS) is a congenital vascular malformation affecting 0.3–0.5% of normal population. These characteristic lesions arise due to the interplay of vascular, neural, and genetic factors. Treatment options include lasers, cosmetic tattooing, electrotherapy, cryosurgery, derma-abrasion, and skin grafting; however, none of these treatment alternatives appears to be satisfactory and is unable to provide consistent, satisfactory responses or even complete cures. Currently, laser is the treatment of choice, as it is comparatively safe and more effective than other procedures. The most commonly used modality is pulsed dye laser (PDL). The literature research includes peer-reviewed articles (clinical trials or scientific reviews). Studies were identified by searching electronic databases (MEDLINE and PubMed) to January 2020 and reference lists of respective articles. Only articles published in English language were included. J Drugs Dermatol. 20(5): doi:10.36849/JDD.5005.

Citation

Regina Fölster-Holst, Ratnakar Shukla, Martin Kassir, Hassan Galadari, Torello Lotti, Uwe Wollina, Stephan Grabbe, Mohamad Goldust. Treatment Update of Port-Wine Stain: A Narrative Review. Journal of drugs in dermatology : JDD. 2021 May 01;20(5):515-518