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    Anti-mitochondrial antibody type 2 is a diagnostic marker of primary biliary cirrhosis and complicates myositis. Myositis with anti-mitochondrial antibody type 2 is clinically characterized by slowly progressive limb, cardiac, and respiratory muscle weakness as well as serum creatinine kinase elevations. However, there has been few cases with eye symptoms. We herein report a 59-year-old woman with anti-mitochondrial antibody type 2 who presented with diplopia and ptosis. Magnetic resonance imaging revealed bilateral ocular muscle enlargement and abnormally high intensities in the lower limb muscles. Corticosteroid therapy improved these symptoms. Myositis with anti-mitochondrial antibody type 2 can present with eye symptoms.


    Taichi Nomura, Kosuke Iwami, Azusa Nagai, Kazufumi Tsuzaka, Ichiro Yabe. Myositis with Anti-mitochondrial Antibody Type 2 with Diplopia and Ptosis. Internal medicine (Tokyo, Japan). 2021 Oct 15;60(20):3325-3328

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    PMID: 33967136

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