Bovine Immune Responses to Moraxella bovis and Moraxella bovoculi Following Vaccination and Natural or Experimental Infections.

John A Angelos, Paola Elizalde, Philip Griebel

The Veterinary clinics of North America. Food animal practice 2021 Jul

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Studies have sought to develop effective vaccines against infectious bovine keratoconjunctivitis (IBK). Most research has focused on parenterally administered vaccines against Moraxella bovis antigens; however, researchers have also included Moraxella bovoculi antigens in vaccines to prevent IBK. Critical knowledge gaps remain as to which Moraxella spp antigens might be completely protective, and whether systemic, mucosal, or both types of immune responses are required for protection against IBK associated with Moraxella spp. Immune responses to commensal Moraxella spp residing in the upper respiratory tract and eye have not been analyzed to determine if these responses control colonization or contribute to IBK. Copyright © 2021 Elsevier Inc. All rights reserved.

Citation

John A Angelos, Paola Elizalde, Philip Griebel. Bovine Immune Responses to Moraxella bovis and Moraxella bovoculi Following Vaccination and Natural or Experimental Infections. The Veterinary clinics of North America. Food animal practice. 2021 Jul;37(2):253-266