Drugs of Abuse-Opioids, Sedatives, Hypnotics.

Keith Azevedo, Molly Johnson, Michael Wassermann, Jessica Evans-Wall

Critical care clinics 2021 Jul

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Over the last 2 decades, prescription and nonprescription substance use has significantly increased. In this article, 3 particular drug classes-opioids, sedatives, and hypnotics-are discussed. For each class, a brief history of the agent, a description of relevant pharmacology, the clinical presentation of overdose, the management of specific drug overdoses, and a summary of salient points are presented. The intent is to provide a clinically relevant and comprehensive approach to understanding these potential substance exposures in order to provide a framework for management of opioid, sedative, and hypnotic overdoses. Copyright © 2021 Elsevier Inc. All rights reserved.

Citation

Keith Azevedo, Molly Johnson, Michael Wassermann, Jessica Evans-Wall. Drugs of Abuse-Opioids, Sedatives, Hypnotics. Critical care clinics. 2021 Jul;37(3):501-516