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Thibault et al (2021) elucidate key signalling events mediating metastatic evolution in pancreatic ductal adenocarcinoma (PDAC) by demonstrating a role of PI3Kα in the regulation of macro-metastatic disease and a corresponding pro-tumoural immune response supporting disease progression. © 2021 Mayo Clinic. Published under the terms of the CC BY 4.0 license.


Glancis Luzeena Raja Arul, Martin E Fernandez-Zapico. PI3Kα targeting, nipping pancreatic cancer evolution in the bud. EMBO molecular medicine. 2021 Jul 07;13(7):e14362

PMID: 34057823

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