Advances in autoantibodies and primary Sjogren's syndrome: An update].

One of the hallmarks of primary Sjogren's syndrome (pSS) is the presence of various autoantibodies in patients' serum, including traditional autoantibodies for disease diagnosis and classification, autoantibodies associated with other autoimmune diseases, and the novel autoantibodies identified from mouse models. The autoantibodies are closely related to the diagnosis, prognosis, and clinical manifestations of pSS. There are significant differences in the prevalence and clinical correlations between anti-Ro60 antibody and anti-Ro52 antibody. Also, the novel autoantibodies play an important role in the diagnosis and classification of pSS. These advances further improve the accuracy of pSS diagnosis and provide references for basic and clinical research.

Citation

Xin Cai, Yaxin Zhou, Hongxia Li, Zhenbiao Wu. Advances in autoantibodies and primary Sjogren's syndrome: An update]. Xi bao yu fen zi mian yi xue za zhi = Chinese journal of cellular and molecular immunology. 2021 Jun;37(6):563-568

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PMID: 34060451

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