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    Heterotopic pregnancy is the condition where both intrauterine and ectopic pregnancy are present. It rarely occurs after natural conception, but is more common with assisted reproductive techniques, when more than one embryo is transferred. Quadruplet heterotopic pregnancy is exceedingly rare. A literature review was conducted aiming to highlight the diagnosis difficulties and the management options in heterotopic quadruplet pregnancies. Nine relevant studies were identified by researching PubMed up to 2021 for "heterotopic quadruplet pregnancy", "quadruplet intrauterine and ectopic pregnancy", "synchronous intrauterine and ectopic pregnancy". In this paper, we present a case of heterotopic quadruplet pregnancy and address the difficulty in diagnosing this condition and make formal recommendations.

    Citation

    Brîndușa Cimpoca, Amira Moldoveanu, Nicolae Gică, Corina Gică, Anca Marina Ciobanu, Anca Maria Panaitescu, Dana Oprescu. Heterotopic Quadruplet Pregnancy. Literature Review and Case Report. Medicina (Kaunas, Lithuania). 2021 May 12;57(5)

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    PMID: 34065925

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