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    Wan et al. (2021) establish a powerful new platform to measure the dynamics of transcription and splicing of endogenous genes in single cells in real time. Combining real-time measurements with multiple deep-sequencing tools reveals an unexpectedly high amount of spliceosome activity, prompting a reconsideration of current models of how introns are removed from pre-mRNA. Copyright © 2021 Elsevier Inc. All rights reserved.


    Donny D Licatalosi. Intron removal by the spliceosome: A solo job or a team effort? Molecular cell. 2021 Jun 03;81(11):2275-2277

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    PMID: 34087179

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