Initial Failure of Pristinamycin Treatment in a Case of Multidrug-Resistant Mycoplasma genitalium Urethritis Eventually Treated by Sequential Therapy.

Romain Palich, Marie Gardette, Cécile Bébéar, Éric Caumes, Sabine Pereyre, Gentiane Monsel

Sexually transmitted diseases 2021 Nov 01

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We present a case of persistent Mycoplasma genitalium urethritis with documented macrolide and fluoroquinolone resistance, and we describe the A2062T mutation in the 23S rRNA gene, possibly associated with pristinamycin resistance. After several treatment failures and loss of the A2062T mutation, M. genitalium urethritis was finally cured by a sequential antibiotic treatment including minocycline. Copyright © 2021 American Sexually Transmitted Diseases Association. All rights reserved.

Citation

Romain Palich, Marie Gardette, Cécile Bébéar, Éric Caumes, Sabine Pereyre, Gentiane Monsel. Initial Failure of Pristinamycin Treatment in a Case of Multidrug-Resistant Mycoplasma genitalium Urethritis Eventually Treated by Sequential Therapy. Sexually transmitted diseases. 2021 Nov 01;48(11):e163-e164