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A new approach for the preparation of carbamates via the copper-catalyzed cross-coupling reaction of amines with alkoxycarbonyl radicals generated from carbazates is described. This environmentally friendly protocol takes place under mild conditions and is compatible with a wide range of amines, including aromatic/aliphatic and primary/secondary substrates.

Citation

Song-Ning Wang, Guo-Yu Zhang, Adedamola Shoberu, Jian-Ping Zou. Copper-Catalyzed Coupling of Amines with Carbazates: An Approach to Carbamates. The Journal of organic chemistry. 2021 Jul 02;86(13):9067-9075

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PMID: 34139836

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