Comparison of HIV therapy applied in urban and rural areas - results of a retrospective study between Berlin and Greifswald/ Vorpommern].

Lisa Wunsch, Michael Jünger, Martin Obermeier

MMW Fortschritte der Medizin 2021 Jun

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The steady development of the antiretroviral therapy (ART) has led to a significant change in the demands on the quality of care. There are different regional challenges.It is a non-interventional, bicentric correlation study in the form of a retrospective data analysis including data of 43 HIV-positive patients in Greifswald and 1669 in Berlin. All variables were evaluated with R. Statistical significance was assumed at a p-value of ≤ 0.05.The immunological parameters showed a significantly lower CD4+ T-lymphocyte cell count in patients from Greifswald compared to those from Berlin (B: 516/μl blood; G: 266/μl blood; p < 0.001). The supply of ART was > 80% (B: 153/184 [83.15%]; G: 36/41 [87.8%]; p = 0.64) in both cohorts and led to a permanent (> than 4 quarters) drop of the viral load below the detection limit in 115/184 [62.25%] patients in Berlin and 23/41 [56.09%] patients in Greifswald (p = 0.008).This study has shown that the quality of care for HIV-infected patients in both urban and rural areas is of a high standard and carried out in accordance with the guidelines.

Citation

Lisa Wunsch, Michael Jünger, Martin Obermeier. Comparison of HIV therapy applied in urban and rural areas - results of a retrospective study between Berlin and Greifswald/ Vorpommern]. MMW Fortschritte der Medizin. 2021 Jun;163(Suppl 2):28-35