Investigation of alterations in phospholipids during the production chain of infant formulas via HILIC-QTOF-MS and multivariate data analysis.

Yan Tang, Xuechun Sun, Haiyue Hou, Augustine Atta Debrah, Mengyu Wang, Fengxia Zhang, Zhenxia Du

Food chemistry 2021 Dec 01

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Phospholipids play a key role in infant nutrition and cognitive function. In this study, hydrophilic interaction liquid chromatography coupled to quadrupole time-of-flight mass spectrometry method was firstly developed to analyze the composition of phospholipids. Then we characterized and quantified phospholipids extracted from raw, pasteurized, homogenized, and spray-dried milk to investigate the effect of the technological process on the composition of the phospholipids. Results indicate that the composition of the phospholipids underwent minor changes after pasteurization, while the concentration of phospholipids was significantly affected by the spray-drying process, especially phosphatidylethanolamine and phosphatidylinositol. Multivariate data analysis further verified the results and indicated that phospholipids containing polyunsaturated fatty acids had undergone significant changes during the production chain, especially in spray-drying. This work reveals the changes of phospholipids composition during the production chain of infant formulas and serve as a reference for the subsequent optimization of infant formulas to meet nutritional need of infants. Copyright © 2021 Elsevier Ltd. All rights reserved.

Citation

Yan Tang, Xuechun Sun, Haiyue Hou, Augustine Atta Debrah, Mengyu Wang, Fengxia Zhang, Zhenxia Du. Investigation of alterations in phospholipids during the production chain of infant formulas via HILIC-QTOF-MS and multivariate data analysis. Food chemistry. 2021 Dec 01;364:130414