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    In this case report, we described a patient admitted with persistent methamphetamine-induced psychotic symptoms, accompanied by negative symptoms, who appeared to respond to cariprazine treatment regarding his psychotic and craving symptoms. To our knowledge, no cariprazine-related data has been published about these type of patients. Our case suggests that cariprazine may improve both psychotic and addictive symptoms in subjects with persistent substance-induced psychotic disorders. Notably, our patient reported an abrupt decrease in substance craving and use, and an improvement in positive and negative psychotic symptoms. Although it is not possible to generalize the observations and findings gathered with this single case, it detected a potential effect of cariprazine on a drug naïve patient with persistent psychotic symptoms induced by methamphetamine for the first time.


    Valerio Ricci, Gabriele Di Salvo, Giuseppe Maina. Remission of persistent methamphetamine-induced psychosis after cariprazine therapy: presentation of a case report. Journal of addictive diseases. 2022 Jan-Mar;40(1):145-148

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    PMID: 34180372

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