Room-temperature controllable synthesis of hierarchically flower-like hollow covalent organic frameworks for brain natriuretic peptide enrichment.

Wende Ma, Guorong Li, Chao Zhong, Yixin Yang, Qianqian Sun, Dan Ouyang, Wei Tong, Wenchang Tian, Lan Zhang, Zian Lin

Chemical communications (Cambridge, England) 2021 Jul 27

filter terms:

A facile strategy was introduced for room-temperature controllable synthesis of hierarchically flower-like hollow COFs (FHF-COFs). Furthermore, the universality for synthesis of the HFH-COFs was validated by altering the building units. Inspired by the unique morphology, extremely large surface area and good chemical stability, HFH-COFs could serve as an attractive adsorption probe by loading with gold nanoparticles and be applied to enrichment of brain natriuretic peptide from human serum. This work opens up a whole new approach for controllable synthesis of the HFH-COFs at room temperature and expands the application of COFs as a promising enrichment probe for complex biological samples.

Citation

Wende Ma, Guorong Li, Chao Zhong, Yixin Yang, Qianqian Sun, Dan Ouyang, Wei Tong, Wenchang Tian, Lan Zhang, Zian Lin. Room-temperature controllable synthesis of hierarchically flower-like hollow covalent organic frameworks for brain natriuretic peptide enrichment. Chemical communications (Cambridge, England). 2021 Jul 27;57(60):7362-7365